I am using notmuch as my main email client. One of the main things that notmuch doesn't handle currently, and which I have to regularly use another email client for, is accepting or rejecting calendar invitations from MS Teams (I know, I hate it too... Corporate sux).
When I accept an invitation the event on an email client (even a non-MS one), the event is automatically added to my calendar and I think an email is sent to the event organizer.
Is it possible to replicate this in notmuch? Is it a simple case of replying with "Accepted" in the title?