lainchan / hum

Gap 43 Protein

Six · 2021-12-27 00:51
Typically when talking about neutrophic proteins BDNF is mentioned on a scattered redd!t thread which deals with generation of new neurons. Another protein which is even less mentioned is I can't seem to google anymore (some phrases in google pops up a list of important brain growth proteins; forgot what it was.) A rather unknown protein is called Gap 43 Protein which has limited information or talk about online which is responsible for neuroplasticity and the reason why children learn much better than adults do. If one were able to replicate the protein or the precursors to the protein in the brain it could re-enable the learning enjoyment/capability as if you were eight years old. Are there any possible resources which can delve into this protein or similar proteins? A similar idea was presented with a chemical known as Dihexa which elevated BDNF by a factor of four. As that is simply increasing neuron count a chemical in the realm of increasing gap 43 protein may be more beneficial in day-to-day life especially when it comes to tech/coding/etc.
Yuki Nagato · 2021-12-27 02:28
>If one were able to replicate the protein or the precursors to the protein in the brain it could re-enable the learning enjoyment/capability as if you were eight years old. That is not necessarily a good thing. You might become a quicker learner, but once you reach a certain level of advancement in any skill being a quick learner stops being so important as having dedication and a thorough, methodical approach.
Erik Johansson · 2021-12-27 05:29
>>54678 Neuromodulating this might have interesting implications, but consider that more plasticity is not in general, a desirable thing as it may have deleterious effects on crystalised intelligence, personality, emotional development, physical coordination, "muscle memory", etc, etc. One potentially interesting use may be in the treatment of trauma and personality disorders, but I am not an expert in neither their environmental, nor their, organic origins so I can only speculate
Batou · 2021-12-27 08:22
There are drugs that achieve a similar effect but work by dissolving the extracellular matrix around neurons. Don't remember the name, but it was being tested as a way to learn languages without an accent - the primary cortical areas for perception and action becomes quite fixed in adulthood. Many other cortical areas are quite plastic however so I'm not so sure it would help with learning in general; Human brains are already juvenile and plastic. If you simply want to learn more then just do that... plenty of people enjoy learning and are good at it late into life (every university has a few of these old professors that are very sharp and curious). The method of learning switches from the spongy uncritical learning of a child to one that relies on drawing connections to existing knowledge, which imo is more useful anyway.
Drano · 2021-12-27 13:13
>>54682 There is a lot of junk knowledge from when we were kids such as knowing the names of the Backstreet Boys and the tales of the Berenstain Bears. Re-writing the neural imprinting of useless information may improve performance of the brain which using the name amount of dendritic connections and neuron count. Then again this would be a demonstration of luck and/or selective neuron imprint rewriting.