opiod jackidemic

I have been researching gooning. A big realization that I have come to, was that the molecules (endorphins) released during the said activity are basically opioids, just endogenous ones. Specifically, Beta-Endorphins. The only difference between it and lets say a conventional opioid like Morphine/Heroine/Fent is the potency, specificity and the size. One of the coolest things I have recently realized is that the size difference between endogenous and exogenous opioids is huge, which is the main reason why synthetic Beta-Endorphin cannot act like a normal opiod(this molecule cannot pass through the blood brain barrier), basically the huge size of the endorphin causes it to me metabolized easily in the brain. Nonetheless, it is interesting that a gooner is just an avid opiod user! Wdyt?

>>20532 isn't it crazy that we're all high on neurotransmitters all the time. I am, you are, and so were adolf hitler and jesus christ of nazareth. duuuuude

It is thought it can actually be endocannabinoids https://pmc.ncbi.nlm.nih.gov/articles/PMC10264596/

Did you save some sources of your reading OP I would like take a look at it too

. also beta phenethylamine which gets rapidly broken down by maob enymes

even make our own version of ghb.an illness (-hydroxybutyric aciduria) that shows evidence that certain rare people can make a bit too much of it y-hydroxybutyric aciduria

>>20537 This is general info, u can just look up Beta-Endorphin, Blood Brain Barrier on Wikipedia.

>gooner Frfr no cap shi be bussing nuts and making me feel sum typeah way like zaza n shiet

>>20532 Now you are learning part of the secret. Continue down the rabbit hole of endogenous opioids and you will see many more wonders than just these.

This is not true. Beta-endorphin doesn't seem to increase at all during sex and high levels of beta-endorphin are actually associated with lack of interest in sex. A lot of the literature seems to speculate this is related to the asexuality seen in long-term opioid users, as beta-endorphin primarily binds to mu-opioid receptors that opioid drugs do. First image: Endorphins, Sexuality, and Reproduction - Marjan Khajehei Second image: Neuroendocrinologic developments in sexuality: Beta-endorphins in sexual desire phase disorders - J. Dudley Chapman.

fake and gay. take heroin instead.

>>20732 based based based based

Im not an expert but my issue with this is that the gooning edging cycle is also highly dopamine reward chase focused which is why stimulants often allow someone to zerk off for so long. Speaking as someone who be gooning when I take stims, the chase and getting lost in a fantasy is actually more important. On stims the fantasies have to be more and more deranged, often things when sober I have flat out 0 interest in. Opening up tab after tab searching around more time is actually spent constructing this fantasy than jerking off. It used to also renove my refractory period so it would be a cycle of jerk off cum jerk off cum but increasingly just perusing various hardcore pornography became the greater interest. I dont know how a nat gooner does it but I always imagine its similar and the reward they get from jerking off is just far greater than me. Its funny I have a girlfriend and a normal life and these fantasies rarely bleed into relationships because I simply dont want them to, them being fantasy is what makes them engaging. Ive also taken opiates and the thing about opiates is its like a shortcut to just get a reward a warm fuzzy feeling and motivation or alternatively totally peaceful unmotivation. Ive noticed actually when people (not just me) first take them they often feel like the opiate didnt do anything because I think to be cognizant of euphoria and the good feelings your brain first has to connect them to being caused by something in this case a pill. With stims on their own if you just sat there it could actually feel bad even though there is feel good chemicals, but the minute you engage in something you already like doing or even something you normally dont it feels great even first time because that pathway already exists. It takes a bit for you to start to crave the stim itself and end up ruining it like me where I cant buy them often cause il just jerk off for hours by myself instead of working on something amazing or chatting with people. Even in that case though jerking off is still an activity you still have to do something. Opiates you can do absolutely nothing and feel great. If you could make gooning like opiates where you can say press a button to instantly cum as much as you want though some gooners would press it till they die I think many actually wouldnt because watching the porn and edging or even just imagining scenarios is a crucial part and is what makes masturbating feel so distinct from opiates even if the chems are similar. The context is everything. The build up is the only thing that makes ejaculation feel like a release and not just a flood of warm fuzzy feels. That context is also why some because of trauma or whatever else take no pleasure in sex or ejaculation or why some get sad and cry after sex and others jump out of bed and get to work like nothing happened.

>>20731 Would that mean a mu receptor antagonist can increase sexuality?

>>20734 Little thing I forgot to add to this, this could just be me but for awhile now ive tried to figure out in these goon sesh's that maybe happen once every few weeks to once every few months, what exactly am I trying to get. Ive done it enough times now I know it ends in just wasted time and a bit of irrational paranoia that someone knows what I was doing or I accidentally sent someone something. Im older and do like sex better than jerking off at this point so its never going to feel as good as it used to on both fronts. Ive long known beating yourself up doesnt work because there is reasons or things we think we stand to gain in even our worst habits, so earnestly I asked myself why do I do this. I have access to opiates if I so pleased so if it was about feeling good id just buy some of those. Its always vaguely like im trying to find something out about myself or reconcicle with something. Desires a fickle thing but this specifically odd to me because its not like wanting to be rich and then once your rich you want something else and such is folly of human. I said "more and more deranged" but I basically hit a cap on the level of deranged or more just bizarre porn im acceptable with awhile ago so it truly is chasing the same thing every time and just rotating. When im bored of jerking off to like drawings of guys gutpunching femboys il sometimes just move to like videos of girls kissing with nothing going on next time and then after that i might just jerk off to my imagination but then next time its a vid of someone masturbating in a public park and ripping ass. I have two theories and maybe both are correct, a girl I dated once was also actually kind of a gooner and it seemed to come out of her own sexuality being a bit of a mystery to her. Im just straight mostly that part isnt a mystery but both my mom and my dad didnt talk about sex and I never heard or saw them have sex. I was also a late bloomer and often in attempts to fit in and talk about sex when everyone was blooming id say some weird soykaf thay would be met with discomfort that I couldnt relate to cause I didnt have the feelings yet to know what disturbed them or was normal. I think this manifsted as a neurotic idea that my desires were unnatural and needed to be addressed when felt immediately so they didnt crop up elsehwere and later that turned into masturbation being a source of comfort and safety. These days this looks like my little stim benders cropping up when im getting very close to someone new and a worry I might cheat on whoever im with, with this new person. Thus if I just fall into depravity for a few weeks and fully explore myself sexually maybe il be so sick of it all that even if the new person tries to flirt with me I wont even be in the mood to reciperocate or even notice or will discover something about why suddenly I find this new person attractive. My other kind of linked theory, and this is more applicable to your average gooner, is that to all of us our sexuality is a bit of this question mark which is why sex and masturbation continue to be engaging and rewarding no matter how many times we do it more or less as we never have it figured out. Its especially why sex is engaging I think because someone elses sexuality is also involved and theres a little hope when seen from the outside they can tell you something and often they do. To the isolated gooner then its just especially a mystery but also they are too scared to invite or too scared to figure out how to invite someone into that mystery and make it less of one. As my sex drive has become less of a mystery to me the amount of fantasies I can actually entertain kind of shrink which is also why often a stimfap sesh involves more trying to find a fantasy i can jerk off to than actually jerking off as il find a flaw in one before i even start smashing my dick off. Weirdly this somehow has never translated to am increase in boredom with real normal sex for me. In short not to discredit you these chemicals are very real and your connection has facts and truth in it but I think theres a reason many gooners choose gooning over opiates (or choose gooning + a non opiate drug) beyond just accessibility and thats what im getting at here.

>>20532 Keep in mind its not JUST endo-opis being released. That is one of a series of things, but it is one of the more little known and interesting ones.